The General Clinical Research Center (GCRC) and the Clinical and Translational Research Institute (CTRI) have developed a new program that supports clinically relevant research and technology through collaboration. Multiple annual awards of up to $25,000 will be available to CTRI and GCRC researchers. Proposals are now solicited for the following types of awards:
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Pilot Clinical Studies—Patient-oriented studies designed to test novel hypotheses, therapeutic targets, or diagnostic agents. Projects could include multidisciplinary interactions and use of biomarker or imaging endpoints. Studies to improve access to state-of-the-art diagnosis and treatment for traditionally underserved populations are also appropriate. Additionally, projects that improve clinical design, biostatistics, ethics, informatics, or regulatory pathways vis-à-vis translational research are sought. Additional consideration is given to awards that include a laboratory scientist as a co-investigator. Up to $25,000 per award.
- Pilot Translational Studies—Pre-clinical studies designed to validate a therapeutic target that uses in vivo or in vitro models. These projects require a clinical researcher to serve as co-PI to assure disease relevance. Up to $25,000 per award.
- Pilot Innovative Technology Projects—Projects that develop new technology to assess disease susceptibility, pathogenesis, or severity that could potentially be applicable to clinical research. A particular focus on biomarker or imaging modalities is anticipated. Additional consideration is given to projects that include a clinical researcher to serve as co-investigator to assure disease relevance. Up to $50,000 per award.
Collaborative projects from investigators below the rank of Professor will receive priority. Proposals will be accepted from investigators at UCSD, Rady Children’s Hospital, SDSU, LIAI, Salk, Burnham, and J. Craig Venter Institute, eligible to be principal investigators under the policies of their respective organizations. UCSD PIs must have a fulltime faculty appointment.
The deadline for receipt of proposals is November 30, 2008. At this time requested documents are to only include an abstract (500 words, either as an attached pdf document or within the email. Abstracts longer than 500 words will NOT be reviewed) an NIH-style Biosketch, including current grant support of the principal investigator(s) and a proposed budget. Preliminary data are not required; the emphasis is on innovation, not past results. The abstract should state the project title, principal investigator(s), significance of the research, specific aims, hypothesis and summary methodology. Please indicate the Program component most closely aligned with the proposal; i.e., Clinical Studies, Translational Studies or Innovative Technology.
The review will be conducted by a panel of internal and external scientists working in translational research. The review priorities include: 1) significance of the research and its translational relevance; 2) scientific quality; 3) feasibility; 4) probability that the work will yield important new information, technology or service; 5) qualifications of the principal investigator and collaborators.
The application is to be submitted by e-mail to Melinda Richards at mrichards@ucsd.edu. Questions should be addressed to Dr. Sonia Ancoli-Israel at sancoliisrael@ucsd.edu
Application Deadline: November 30, 2008
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